RNA interference screening demystified

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RNA interference screening demystified

Genetic screens, where the effects of modifying gene function on cell behaviour are assessed in a systematic fashion, have for some time provided useful information to those interested in disease pathogenesis and treatment. Genetic screens exploiting the phenomenon of RNA interference (RNAi) are now becoming commonplace. This article explains the different RNAi screen formats and describes some...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 2009

ISSN: 0021-9746

DOI: 10.1136/jcp.2008.058735